Best Fertility Centre – Dr. Swapna Naik

PGS(Pre Implant Genetic Surgery)

What is PGS(Preimplantation Genetic Screening)?

PGS is a procedure used during IVF to screen embryos for chromosomal abnormalities before they are implanted into the uterus. This screening helps identify embryos with the correct number of chromosomes, increasing the likelihood of a successful pregnancy and reducing the risk of miscarriage.

Why Consider PGS? 

PGS is recommended for individuals or couples with a history of recurrent miscarriages, advanced maternal age, or those at risk of passing on genetic disorders. By selecting embryos with the highest potential for implantation and healthy development, PGS improves IVF success rates and reduces the chance of genetic abnormalities.

How Does PGS Work?

  1. Embryo Biopsy: After fertilization, a small number of cells are removed from each embryo for genetic analysis.

  2. Genetic Testing: The cells undergo comprehensive genetic testing to assess chromosome numbers and structure, identifying abnormalities such as aneuploidy (abnormal chromosome count).

  3. Embryo Selection: Based on the PGS results, only embryos deemed chromosomally normal are selected for transfer into the uterus during IVF.

Benefits of PGS:

  • Increased IVF Success Rates: Selecting chromosomally normal embryos improves implantation rates and reduces miscarriage risk.
  • Reduction in Multiple Pregnancies: By transferring fewer embryos of higher quality, the risk of multiple pregnancies (and associated complications) is minimized.
  • Peace of Mind: PGS provides reassurance by identifying embryos less likely to result in miscarriage or genetic disorders, helping couples make informed decisions.
Considerations and Limitations: 

While PGS offers significant benefits, it may not guarantee pregnancy success in all cases. Factors such as embryo quality, maternal age, and underlying fertility issues can influence outcomes. Additionally, PGS does not screen for all genetic conditions or guarantee the absence of all abnormalities.


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