Best Fertility Centre – Dr. Swapna Naik

In Vitro Maturation (IVM)

What is In Vitro Maturation (IVM)? 

In Vitro Maturation (IVM) is a fertility treatment technique that involves retrieving immature eggs from the ovaries and allowing them to mature in a laboratory setting before fertilization. This approach is particularly beneficial for women with certain medical conditions, PCOS (Polycystic Ovary Syndrome), or those at risk of ovarian hyperstimulation syndrome (OHSS).

How Does IVM Work?

  1. Ovarian Stimulation: Unlike traditional IVF, IVM typically involves minimal or no ovarian stimulation using fertility medications. This reduces the risk of complications associated with high hormone levels.

  2. Egg Retrieval: Immature eggs are retrieved from the ovaries using a minimally invasive procedure similar to that used in standard IVF.

  3. In Vitro Maturation: The immature eggs are cultured in a laboratory environment, where they are carefully monitored and allowed to mature over a period of 24-48 hours.

  4. Fertilization and Embryo Transfer: Once matured, the eggs are fertilized using either conventional insemination or intracytoplasmic sperm injection (ICSI). The resulting embryos are then transferred to the uterus for implantation.

Benefits of IVM:

  • Reduced Ovarian Stimulation: Minimizing hormone exposure lowers the risk of ovarian hyperstimulation syndrome (OHSS) and other related complications.
  • Fertility Preservation: IVM provides an option for women who need to undergo urgent medical treatments that may impact fertility, such as chemotherapy or radiation.
  • Alternative for PCOS Patients: Women with PCOS, who are often at higher risk of ovarian complications, may benefit from IVM due to its gentler approach to ovarian stimulation.

Considerations and Success Rates: 

While IVM offers promising benefits, success rates can vary based on factors such as age, ovarian reserve, and underlying fertility issues. It may not be suitable for everyone, and your fertility specialist can help determine if IVM is the right option for you based on a thorough evaluation.

In Vitro Maturation (IVM) represents a progressive alternative to traditional IVF, offering a gentler approach to fertility treatment with fewer risks of complications associated with ovarian stimulation. By exploring IVM with a qualified specialist, individuals can pursue their dreams of parenthood with confidence and tailored medical guidance.


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